LIST BY YEAR: 2018 - now | 2017 and earlier

*Equal contribution

Authors in BOLD denote Hu Lab members

Du W*, Verma A*, Ye Q, Du W, Lin S, Yamanaka A, Klein OD, Hu JK. (2024) Myosin II mediates Shh signals to shape dental epithelia via control of cell adhesion and movement. PLOS Genetics 20(6): e1011326 PMCID: PMC11192418 Click to view

Shroff NP, Xu P, Kim S, Shelton ER, Gross BJ, Liu Y, Gomez CO, Ye Q, Drennon TY, Hu JK, Green JBA, Campàs O, Klein OD. (2024) Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development. Nat Cell Biol. 26:519–529 Click to view

Bermudez A, Negrete Muñoz S, Blaik R, Rowat AC, Hu JK*, Lin NYC*. (2023) Using Histologic Image Analysis to Understand Biophysical Regulations of Epithelial Cell Morphology. The Biophysicist 4(2) Click to view

Thooyamani SA*, Shahin E*, Takano S, Sharir A*, Hu JK*. (2023) Using Ex Vivo Live Imaging to Investigate Cell Divisions and Movements During Mouse Dental Renewal. J Vis Exp (200):10.3791/66020 PMCID: PMC10874233. Click to view

Hu JK. (2023) Nail mesenchyme: Tipping the hand on regeneration. Cell Rep. 42:111960 Click to view

Ye Q, Bhojwani A, Hu JK. (2022) Understanding the development of oral epithelial organs through single cell transcriptomic analysis. Development 149 (16): dev200539 Click to view

Du W, Bhojwani A, Hu JK. (2021) FACEts of mechanical regulation in the morphogenesis of craniofacial structures. Int. J. Oral Sci. 13:4 PMCID: PMC7865003. Click to view

Kindberg A, Hu JK*, Bush JO*. (2020) Forced to communicate: Integration of mechanical and biochemical signaling in morphogenesis. Current Opinion in Cell Biology. 66:59–68. PMCID: PMC7577940. Click to view

Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, Ferreira DDS, Ma HY, Duwaerts CC, Espanol-Suner R, Wei L, Newcomb B, Mileva I, Canals D, Hannun YA, Chung RT, Mattis AN, Fuchs BC, Tager AM, Yimlamai D, Weaver VM, Mullen AC, Sheppard D, Chen JY. (2020) Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice. Sci. Transl. Med.12(557):eaay8798. PMCID: PMC7976849

Sharir A, Marangoni P, Zilionis R, Wan M, Wald T, Hu JK, Kawaguchi K, Castillo-Azofeifa D, Epstein L, Harrington K, Pagella P, Mitsiadis T, Siebel CW, Klein AM, Klein OD. (2019) A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage. Nat Cell Biol. 21(9):1102-1112. PMCID: PMC6935352. Click to view

Calamari ZT, Hu JK, Klein OD. (2018) Tissue mechanical forces and evolutionary developmental changes act through space and time to shape tooth morphology and function. Bioessays. 40(12):e1800140. PMID: 30387177. Click to view

Hu JK, Du W, Shelton S, Oldham M, DiPersio CM, Klein OD. (2017) An FAK-YAP-mTOR signaling axis regulates stem cell-based tissue renewal in mice. Cell Stem Cell 21(1):91-106 PMCID: PMC5501749. Click to view

Du W*, Hu JK*, Du W, Klein OD. (2017) Lineage tracing in developing teeth reveals two mechanisms for building signaling centers. J. Biol. Chem. 292(36):15062-15069. PMCID: PMC5592681. Click to view

Li CY*, Hu JK*, Lu H, Lan J, Du W, Galicia N, and Klein OD. (2016) αE-catenin inhibits YAP/TAZ activity to regulate signaling center formation during tooth development. Nature Communications 7:12133. PMCID: PMC4947177. Click to view

Chavez MG, Hu JK, Seidel K, Li C, Jheon A, Naveau A, Horst O, Klein OD. (2014) Isolation and culture of dental epithelial stem cells from the adult mouse incisor. Journal of visualized experiments: JoVE (87). PMCID: PMC4141628

Hu JK, Mushegyan V, and Klein OD. (2014) On the cutting edge of organ renewal: Identification, regulation, and evolution of incisor stem cells. Genesis 52(2):79-92. PMCID: PMC4252016. Click to view

Tschopp P, Sherratt E, Sanger TJ, Groner AC, Aspiras AC, Hu JK, Pourquié O, Gros J, Tabin CJ. (2014) A relative shift in cloacal location repositions external genitalia in amniote evolution. Nature 516(7531):391-4. PMCID: PMC4294627

Biehs B*, Hu JK*, Jung H, Strauli NB, Sangiorgi E, Heber R-P, Goodwin AF, Ho S, Capecchi MR, Dasen J, and Klein OD. (2013) Bmi1-mediated repression of Inka/Arf and Hox genes controls stem cells in the rodent incisor. Nature Cell Biology 15(7):846-52. PMCID: PMC3735916. Click to view

Hu JK, McGlinn E, Harfe BD, Kardon G, and Tabin CJ. (2012) Autonomous and non-autonomous roles of hedgehog signaling in regulating limb muscle formation. Genes and Development 26, 2088-2102. PMCID: PMC3444734

Cooper KL*, Hu JK*, ten Berge D, Fernandez-Teran M, Ros MA, and Tabin CJ. (2011) Initiation of proximal-distal patterning in the vertebrate limb by signals and growth. Science 332, 1083-1086. PMCID: PMC3258580

Gros J, Hu JK, Vinegoni C, Feruglio PF, Weissleder R and Tabin CJ. (2010) WNT5A/JNK and FGF/MAPK pathways regulate the cellular events shaping the vertebrate limb bud. Curr. Biol. 20, 1993-2002. PMCID: PMC2998074.

Schlabach MR, Hu JK, Li M, and Elledge SJ. (2010) Synthetic design of strong promoters. Proc. Natl. Acad. Sci. U.S.A. 107, 2538-2543. PMCID: PMC2823900.

Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O’Connell DJ, Maas RL, and Tabin CJ. (2009) Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc. Natl. Acad. Sci. U.S.A. 106, 18297-302. PMCID: PMC2775291.

Loscertales M, Mikels AJ, Hu JK, Donahoe PK, and Roberts DJ. (2008) Chick pulmonary Wnt5a directs airway and vascular tubulogenesis. Development 135, 1365-1376. PMID: 18305003.

Horsfield JA, Anagnostou SH, Hu JK, Cho KHY, Geisler R, Lieschke G, Crosier KE, and Crosier PS. (2007) Cohesin-dependent regulation of Runx genes. Development 134, 2639-2649. PMID: 17567667

Hornstein E, Mansfield JH, Yekta S, Hu JK, Harfe BD, McManus MT, Baskerville S, Bartel DP, and Tabin CJ. (2005) The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature438, 671-674. PMID: 16319892